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General description
Theoretical MW is approx. 126 kDa however literature reports observed molecular weight to be 205 kDa to 220 kDa
This gene belongs to the family of reticulon encoding genes. Reticulons are associated with the endoplasmic reticulum, and are involved in neuroendocrine secretion or in membrane trafficking in neuroendocrine cells. The product of this gene is a potent neurite outgrowth inhibitor which may also help block the regeneration of the central nervous system in higher vertebrates. Alternatively spliced transcript variants derived both from differential splicing and differential promoter usage and encoding different isoforms have been identified
Application
Anti-NOGO A Antibody detects level of NOGO A & has been published & validated for use in WB.
Biochem/physiol Actions
Cat. # AB5888 is specific to NOGO A. It does not recognize NOGO B or NOGO C.
Reactivity with other species has not been tested.
Analysis Note
Routinely tested on mouse brain lysate
Legal Information
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
| biological source | rabbit |
| Quality Segment | 100 |
| conjugate | unconjugated |
| antibody form | affinity isolated antibody |
| antibody product type | primary antibodies |
| clone | polyclonal |
| purified by | affinity chromatography |
| species reactivity | mouse, human, rat |
| manufacturer/tradename | Chemicon® |
| technique(s) | western blot: suitable |
| NCBI accession no. | NP_077188.1 |
| UniProt accession no. | Q99P72 |
| shipped in | wet ice |
| target post-translational modification | unmodified |
| Gene Information | mouse ... Rtn4(68585) |
| 长度(mm) | |
| 宽度(mm) | |
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| 重量(kg) |
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