GTP，，10436034001，Roche

销售价： ¥ 1818.50 / 件

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订货号： 0BQ9116

品牌型号： Roche 10436034001

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最小订货量： 1件

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商品介绍
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产品介绍 Product Description

General description

Guanosine-5′-triphosphate (GTP), along with adenosine triphosphate (ATP), cytidine triphosphate (CTP), uridine triphosphate (UTP), and potentially modified UTP, is part of the ribonucleotide mix required for synthesizing messenger RNA (mRNA) during transcription. This process occurs in the presence of RNA polymerase, which catalyzes the formation of RNA from the DNA template using these ribonucleotides.

Application

Guanosine-5′-triphosphate (GTP), cytidine triphosphate (CTP), adenosine triphosphate (ATP), and uridine triphosphate (UTP) are essential nucleotides involved in RNA synthesis. A significant application for these nucleotides is in vitro transcription (IVT) of mRNA, which is widely used in research and experimental studies. IVT kits incorporate these nucleotides to synthesize mRNA from DNA templates, enabling the production of RNA for various applications, including gene expression analysis and functional studies.

However, off-the-shelf kits can restrict researchers’ ability to optimize the concentrations and ratios of these nucleotides according to the specific characteristics of different mRNA molecules such as their composition and length. This constraint can adversely affect the efficiency and quality of the synthesized mRNA.

Consequently, there is increasing interest in developing customizable approaches that allow for greater flexibility in reagent optimization enhancing the performance of IVT reactions to better suit specific experimental needs.

Scalable mRNA Synthesis: Designed for scalable mRNA production, suitable for both small-scale laboratory research and large-scale applications in biotechnology and pharmaceuticals.