- 商品介绍
- 规格参数
- 包装参数
General description
67 kDa
Peroxisome proliferator-activated receptors (PPARs) are nuclear receptors involved in lipid transport and metabolism. As such, their roles in chronic diseases such as diabetes, obesity, atherosclerosis and cancer are heavily investigated. Transcriptional activity of PPARs is regulated by fatty acid binding. Three PPAR isotypes have been identified: a, b and g. PPARg stimulates lipolysis of circulating triglycerides and the subsequent uptake of fatty acids into adipose cells. PPARs can bind to DNA only as a heterodimer with the retinoid X receptor (RXR).
Immunogen
Epitope: isoform 1&2
Synthetic peptide from amino acids 107-121 of human PPAR gamma2.
Application
Anti-PPAR γ Antibody, isoform 1&2 is a Mouse Monoclonal Antibody for detection of PPAR gamma also known as Peroxisome Proliferator Activated Receptor γ & has been validated in ELISA, ICC & WB.
Biochem/physiol Actions
Reacts with human PPAR gamma2. The antibody also reacts with PPAR gamma1 due to immunogen sequence homology. The immunogen shows no homology with PPAR alpha or PPAR beta.
Analysis Note
Control
THP-1 cell lysate, 3T3-L1 cell lysate or U-937 cell lysate
Other Notes
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
Legal Information
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
| biological source | mouse |
| Quality Segment | 100 |
| conjugate | unconjugated |
| antibody form | ascites fluid |
| antibody product type | primary antibodies |
| clone | 1H4, monoclonal |
| species reactivity | human, mouse |
| manufacturer/tradename | Chemicon® |
| technique(s) | ELISA: suitable,immunocytochemistry: suitable,western blot: suitable |
| isotype | IgG1 |
| NCBI accession no. | NM_005037.5,NM_015869.4,NM_138711.3,NM_138712.3 |
| UniProt accession no. | P37231 |
| shipped in | wet ice |
| target post-translational modification | unmodified |
| Gene Information | human ... PPARG(5468) |
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¥ 673.51
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¥ 503.76
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¥ 711.69
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¥ 580.62
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¥ 827.30
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¥ 1669.50
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¥ 3408.16
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¥ 1260.99
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¥ 1310.31
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¥ 1316.02
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