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General description
Epidermal growth-factor receptor (EGF-R) conserved sequence which is identical to v-erbB (95-102). An N-terminal myristoylated membrane-permeable, reversible, and substrate competitive inhibitor that inhibits protein kinase C (IC50 = 5 µM) in intact cells.
Biochem/physiol Actions
Cell permeable: yes
Primary Target
PKC
Product does not compete with ATP.
Reversible: yes
Target IC50: 5 µM against protein kinase C
Packaging
Yes
Physical form
Supplied as a trifluoroacetate salt.
Preparation Note
Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 2 months at -20°C.
Other Notes
Myr-N-Arg-Lys-Arg-Thr-Leu-Arg-Arg-Leu-OH
Ward, N.E., and O’Brian, C.A. 1993. Biochemistry32, 11903.
O’Brian, C.A., et al. 1991. Invest. New Drugs 9, 169.
Legal Information
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
Toxicity: Standard Handling (A)
| Quality Segment | 100 |
| assay | ≥97% (HPLC) |
| form | lyophilized solid |
| manufacturer/tradename | Calbiochem® |
| storage condition | OK to freeze,desiccated |
| solubility | water: 5 mg/mL |
| shipped in | ambient |
| storage temp. | −20°C |
| 长度(mm) | |
| 宽度(mm) | |
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| 重量(kg) |
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¥ 8135.09
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¥ 3812.28
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¥ 20380.83
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¥ 2666.57
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¥ 1564.00
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¥ 3852.13
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¥ 4011.97
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¥ 2406.69
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¥ 44224.19
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