Palmitoylethanolamide,10MG,5043590001,Sigma

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订货号 0BV5882
品牌型号 Sigma 5043590001
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最小订货量 1件
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产品介绍 Product Description

General description

An endogenous lipid that acts as a selective agonist for GPR55 receptors (EC50 = 4, 19 800 and >30 000 nM at GPR55, CB2 and CB1 receptors respectively). Producing robust anti-inflammatory actions by activating PPARα (EC50 = 3 µM).


Biochem/physiol Actions

Primary Target
GPR55 receptor


Preparation Note

Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
Slight warming is required for complete solubilization.


Other Notes

Griffin, G., et al. 2000. J. Pharmacol. Exp. Ther.292, 886.

Lambert, D., et al. 2001. Epilepsia.42, 321.
Lambert, D., et al. 2002. Curr. Med. Chem.9, 663.
Lo Verme, J., et al. 2005. Life Sci.77, 1685.
Re, G., et al. 2005. Vet. J.173, 21.
Ryberg, R., et al. 2007. Br. J. Pharmacol.152, 1092.


Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany


Disclaimer

Toxicity: Standard Handling (A)


技术参数 Specifications
assay≥99% (HPLC)
Quality Segment100
formsolid
manufacturer/tradenameCalbiochem®
storage conditionOK to freeze,protect from light
color white
solubilityDMSO: 20 mM
storage temp.−20°C
SMILES stringN(CCO)C(=O)CCCCCCCCCCCCCCC
InChI1S/C18H37NO2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-18(21)19-16-17-20/h20H,2-17H2,1H3,(H,19,21)
InChI keyHXYVTAGFYLMHSO-UHFFFAOYSA-N
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