Anti-hGITR Antibody, clone 108-17，100UG，MABF240，Sigma 供应商、价格、厂家、报价、规格参数

产品介绍 Product Description

General description

Glucocorticoid-induced TNFR-related protein (hGITR) is also called Tumor necrosis factor receptor superfamily member 18 (TNFRSF18), Activation-inducible TNFR family receptor (AITR) and CD357. hGITR is a receptor for TNFSF18 and is activated by NF-kappa-B through the TRAF2/NIK pathway. hGITR is thought to be involved in activated T-lymphocyte and endothelial cell interactions, as well as regulation of T-cell receptor-mediated cell death. hGITR is expressed in lymph node, peripheral blood leukocytes and at low levels in the spleen.
~ 26 kDa observed. Multiple bands can be observed due to GITR being a monomer & homeodimer in some lysates. Uncharacterized band(s) may appear in some lysates.

Immunogen

Recombinant protein corresponding to human hGITR.

Application

Anti-hGITR Antibody, clone 108-17 is a highly specific mouse monoclonal antibody & that targets GITR & has been tested in western blotting.
Research Category
Inflammation & Immunology
Research Sub Category
Immunoglobulins & Immunology
Western Blotting Analysis: 1.0 µg/mL from a representative lot detected hGITR in 10 µg of mouse lymph node, rat spleen, and rat thymus tissue lysate.

Physical form

Purified mouse monoclonal IgG1κ in buffer containing PBS with 0.05% sodium azide.
Format: Purified
Protein A purified

Preparation Note

Stable for 1 year at 2-8°C from date of receipt.

Analysis Note

Evaluated by Western Blotting in human spleen tissue lysate.

Western Blotting Analysis: 1.0 µg/mL of this antibody detected hGITR in 10 µg of human spleen tissue lysate.

Other Notes

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

技术参数 Specifications

biological source	mouse
Quality Segment	100
conjugate	unconjugated
antibody form	purified immunoglobulin
antibody product type	primary antibodies
clone	108-17, monoclonal
species reactivity	mouse, human, rat
technique(s)	western blot: suitable
isotype	IgG1κ
NCBI accession no.	NP_004186
UniProt accession no.	Q9Y5U5
shipped in	wet ice
target post-translational modification	unmodified
Gene Information	human ... TNFRSF18(8784)

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