Anti-Integrin beta7 Antibody, clone TN114,100UG,MAB2638,Sigma

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订货号 0BV4815
品牌型号 Sigma MAB2638
货期 询货期
最小订货量 1件
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产品介绍 Product Description

General description

Integrin beta7 is an adhesion molecule belonging to the integrin beta chain family. It forms heterodimers with the alpha subunit, most notably the integrin alpha4 and alphaE subunits, functioning to mediate migration and homing of lymphocytes to the gut-associated lymphoid tissue (GALT). The heterodimer formed with alpha4, α4β7, is specifically involved in the homing and migration of lymphocytes to the gut, while αEβ7 is involved in the binding of T lymphocytes to epithelial cells and is induced by TGFβ1. Integrin beta7 has been observed in several different leukocyte lines.
~ 86 kDa


Immunogen

Epitope: Unknown
Purified human integrin beta7 protein.


Application

Anti-Integrin beta7 Antibody, clone TN114 is an antibody against Integrin beta7 for use in FC, IP, IH.
Research Category
Cell Structure
Research Sub Category
Integrins


Biochem/physiol Actions

The antibody recognizes Integrin beta7.


Physical form

Format: Purified
Protein G Purified
Purified armenian hamster monoclonal IgG in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.


Preparation Note

Stable for 1 year at 2-8°C from date of receipt.


Analysis Note

Control
Human peripheral blood mononuclear cells (PBMC′s).
Evaluated by Flow Cytometry in human PBMC′s.

Flow Cytometry Analysis: 1 µg/mL of this antibody detected Integrin beta7 on human PBMC′s.


Other Notes

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.


Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.


技术参数 Specifications
biological sourcehamster (Armenian)
Quality Segment100
conjugateunconjugated
antibody formpurified antibody
antibody product typeprimary antibodies
cloneTN114, monoclonal
species reactivityhuman
technique(s)flow cytometry: suitable,immunohistochemistry: suitable,immunoprecipitation (IP): suitable
isotypeIgG
NCBI accession no.NP_000880.1
UniProt accession no.P26010
shipped inwet ice
target post-translational modificationunmodified
Gene Informationhuman ... ITGB7(3695)
长度(mm)
宽度(mm)
高度(mm)
重量(kg)
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