Luciferase Inhibitor II,5MG,119114-5MGCN,Sigma

销售价: ¥ 1680.43 / 件
在线询价
优    惠: 请询价
订货号 0BV4187
品牌型号 Sigma 119114-5MGCN
货期 询货期
最小订货量 1件
联系我们
  • 400-920-3909
微信扫一扫,手机采购
  • 商品介绍
  • 规格参数
  • 包装参数
产品介绍 Product Description

General description

A 2-arylbenzothiazole compound that acts as an inhibitor against the ATP-dependent Photinus pyralis (lucPpy) and Photuris pennsylvanica (lucPpe) luciferase activity (IC50 = 0.2 and 0.32 µM, respectively, with 10 µM ATP, 10 µM luciferin, and 10 nM respective enzyme). Unlike Luciferase Inhibitor I (Cat. No. 119113), Luciferase Inhibitor II is competitive with respect to luciferin and exhibits reduced potency against lucPpe-based commercial luciferase-luciferin formulations with high luciferin concentration (IC50 = 10 µM against Promega′s Kinase-Glo; ineffective against Kinase-Glo Plus and Kinase-Glo Max; at a 3-fold formulation dilution and 6.77 µM ATP).


Packaging

Packaged under inert gas


Preparation Note

Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.


Other Notes

Auld, D.S., et al. 2009. J. Med. Chem.52, 1450.
Auld, D.S., et al. 2008. J. Med. Chem.51, 2372.


Legal Information

Marketed by Promega Corp. under the registered trademarks.
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany


Disclaimer

Toxicity: Harmful (C)


技术参数 Specifications
Quality Segment100
assay≥95% (HPLC)
formsolid
manufacturer/tradenameCalbiochem®
storage conditionOK to freeze,protect from light
colorpale green
solubilityDMSO: 0.5 mg/mL,ethanol: 3 mg/mL
shipped inambient
storage temp.2-8°C
SMILES string[s]1c2c(nc1c3ccc(cc3)N(C)C)cccc2
InChI1S/C15H14N2S/c1-17(2)12-9-7-11(8-10-12)15-16-13-5-3-4-6-14(13)18-15/h3-10H,1-2H3
InChI keyHYKGLCSXVAAXNC-UHFFFAOYSA-N
长度(mm)
宽度(mm)
高度(mm)
重量(kg)
猜你喜欢

在线
客服

在线客服服务时间:09:00-18:00

微信扫码咨询

客服
热线

400-920-3909
客服服务热线 周一至周五(09:00-18:00)

微信
咨询

微信小程序 7X24小时在线咨询