- 商品介绍
- 规格参数
- 包装参数
General description
The PK136 antibody is specific for mouse NK1.1, a type II transmembrane lectin-like receptor and member of the killer cell lectin-like receptor (KLR) family. NK1.1 is prominently expressed on natural killer (NK) cells, and is correlated with NK cytotoxic effects toward virus-infected cells and tumor cells. NK1.1 is expressed on subsets of NKT cells in certain mouse strains (C57BL/6, FVB/N, and NZB), yet absent from others (AKR, BALB/c, CBA/J, C3H, DBA/1, DBA/2, NOD, SJL, and 129). Putative subsets of NK cells and their expression of NK1.1 antigen are of continuing interest, including NK1.1+/CD117+ (c-Kit) cells reported to be immunosuppressive for CD8+ T cells in a mechanism involving PD-1 and PD-L1 (Ehlers et al. 2012. Endocrinology. 10: 1247).The PK136 antibody may be used for detection of NK1.1 expression on mouse strains including CE, B6, NZB, C58, Ma/My, ST, SJL, and FVB. The antibody is reported to react with an epitope common to NKR-P1B and NKR-P1C alloantigenic forms of NK1.1 (Carlyle et al. 2006. J. Immunol. 176: 7511-7524).
Anti- CD161 (NK1.1) (mouse), redFluor® 710, clone PK136 Antibody is an antibody against CD161 for use in Flow Cytometry.
Analysis Note
This monoclonal antibody was purified from tissue culture supernatant via affinity chromatography. The purified antibody was conjugated under optimal conditions, with unreacted dye removed from the preparation.
Flow Cytometry Analysis: 0.125 μg from a representative lot detected CD161 (NK1.1) in one million C57Bl/6 splenocytes.
Other Notes
Concentration: Please refer to lot specific datasheet.
Legal Information
redFluor is a registered trademark of Tonbo Biotechnologies
| biological source | mouse |
| Quality Segment | 100 |
| conjugate | redFluor® 710 |
| antibody form | purified antibody |
| antibody product type | primary antibodies |
| clone | PK136, monoclonal |
| species reactivity | mouse |
| technique(s) | flow cytometry: suitable |
| UniProt accession no. | P27812 |
| shipped in | wet ice |
| target post-translational modification | unmodified |
| Gene Information | mouse ... Klrb1C(17059) |
| 长度(mm) | |
| 宽度(mm) | |
| 高度(mm) | |
| 重量(kg) |
-
¥ 2019.57
-
¥ 4173.75
-
¥ 8293.41
-
询价
-
询价
-
询价
-
询价
-
¥ 4390.38
-
¥ 1653.62
-
¥ 15214.65
-
询价
-
¥ 8982.64
-
¥ 1156.91
-
¥ 8137.12
-
¥ 4020.77
-
¥ 2869.87
-
¥ 1351.48
-
¥ 5804.96
-
¥ 14985.93
-
¥ 22137.02
微信小程序
7X24小时在线咨询