Milli-Mark® Anti-pan Histone-FITC Antibody, clone H11-4，100TESTS，FCMAB390F，Sigma

销售价： ¥ 3991.08 / 件

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订货号： 0BV3596

品牌型号： Sigma FCMAB390F

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最小订货量： 1件

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产品介绍 Product Description

General description

Antibody recognizes histones H1, H2A, H2B, H3, and H4. Calculated molecular weight for these histones range from 14 to 21 kDa
There are 5 main histone proteins involved in the structure of chromatin in eukaryotic cells. The five major classes of histones are H1/H5, H2A, H2B, H3, and H4. Histones H2A, H2B, H3 and H4 are known as the core histones, while histones H1 and H5 are known as the linker histones. Histones feature a main globular domain and a long N terminal tail which are involved with the structure of the nucleosomes of the ′beads on a string′ structure. They are the chief protein components of chromatin, acting as spools around which DNA winds, and play a role in gene regulation.

Application

This Milli-Mark Anti-pan Histone-FITC Antibody, clone H11-4 is validated for use in FC for the detection of pan Histone.

Biochem/physiol Actions

Due to the highly conserved nature of histones, this antibody is predicted to have wide species reactivity.

Analysis Note

Evaluated by flow cytometry using HeLa cells.

Legal Information

MILLI-MARK is a registered trademark of Merck KGaA, Darmstadt, Germany

技术参数 Specifications

biological source	mouse
Quality Segment	100
conjugate	FITC conjugate
antibody form	purified immunoglobulin
antibody product type	primary antibodies
clone	H11-4, monoclonal
species reactivity	human
manufacturer/tradename	Milli-Mark^®
technique(s)	flow cytometry: suitable
isotype	IgG1
shipped in	wet ice
target post-translational modification	unmodified
Gene Information	human ... H3C1(8350)

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