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- 包装参数
Biochem/physiol Actions
Cell penetrant, potent and selective inhibitor of Plasmodium falciparum myosin A (PfMyoA) and Toxoplasma gondii myosin A (TgMyoA).
KNX-002 is a cell penetrant, potent and selective inhibitor of Plasmodium falciparum myosin A (PfMyoA) and Toxoplasma gondii myosin A (TgMyoA) that has no or little effect on the vertebrate myosins tested. KNX-002 obstructs efficient ATP hydrolysis thus inhibiting motor activity. KNX-002 inhibits parasite motility and growth.
| Quality Segment | 100 |
| assay | ≥98% (HPLC) |
| form | powder |
| color | white to beige |
| solubility | DMSO: 2 mg/mL, clear |
| storage temp. | 2-8°C |
| SMILES string | COC1=CC=C(C2(CC2)NCC3=CNN=C3C4=CC=CS4)C=C1 |
| InChI | 1S/C18H19N3OS/c1-22-15-6-4-14(5-7-15)18(8-9-18)19-11-13-12-20-21-17(13)16-3-2-10-23-16/h2-7,10,12,19H,8-9,11H2,1H3,(H,20,21) |
| InChI key | CXRMCTBDMZVPNE-UHFFFAOYSA-N |
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¥ 6330.00
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¥ 15214.65
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¥ 1568.60
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¥ 51962.23
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