Monoclonal Anti-PKLR, (C-terminal) antibody produced in mouse,100UG,SAB1404211-100UG,Sigma

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订货号 0BN5095
品牌型号 Sigma SAB1404211-100UG
货期 询货期
最小订货量 1件
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产品介绍 Product Description

General description

The protein encoded by this gene is a pyruvate kinase that catalyzes the transphosphorylation of phohsphoenolpyruvate into pyruvate and ATP, which is the rate-limiting step of glycolysis. Defects in this enzyme, due to gene mutations or genetic variations, are the common cause of chronic hereditary nonspherocytic hemolytic anemia (CNSHA or HNSHA). Multiple transcript variants encoding different isoforms have been found for this gene. (provided by RefSeq)


Immunogen

PKLR (AAH25737, 485 a.a. ~ 574 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Sequence
SRYRPRAAVIAVTRSAQAARQVHLCRGVFPLLYREPPEAIWADDVDRRVQFGIESGKLRGFLRVGDLVIVVTGWRPGSGYTNIMRVLSIS


Physical form

Solution in phosphate buffered saline, pH 7.4


技术参数 Specifications
biological sourcemouse
Quality Level100
conjugateunconjugated
antibody formpurified immunoglobulin
antibody product typeprimary antibodies
clone4E12, monoclonal
formbuffered aqueous solution
mol wtantigen ~36.01 kDa
species reactivityhuman
technique(s)indirect ELISA: suitable
isotypeIgG2bκ
NCBI accession no.BC025737
UniProt accession no.P30613
shipped indry ice
storage temp.−20°C
target post-translational modificationunmodified
Gene Informationhuman ... PKLR(5313)
长度(mm)
宽度(mm)
高度(mm)
重量(kg)
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