- 商品介绍
- 规格参数
- 包装参数
General description
DNA (cytosine-5-)-methyltransferase 2 (DNMT2) is a highly conserved protein which is part of the DNA methyltransferase family. It possesses a conserved cysteine residue in its catalytic pocket. The gene encoding it is localized on human chromosome 10p14->p12.
Application
Useful for the study of enzyme kinetics, screening inhibitors, and selectivity profiling.
Biochem/physiol Actions
DNA (cytosine-5-)-methyltransferase 2 (DNMT2) methylates the cytosine-38 residue of the aspartic acid transfer RNA (tRNA-Asp). It has been shown to interact with the anticodon stem and loop. The protein also functions in cellular physiology and stress response. It is significantly expressed in cancers.
Physical form
Formulated in 25 mM Tris-HCl, pH 8.0, 100 mM NaCl, 0.05% Tween-20 and 10% glycerol.
Preparation Note
Thaw on ice. Upon first thaw, briefly spin tube containing enzyme to recover full content of the tube. Aliquot enzyme into single use aliquots. Store remaining undiluted enzyme in aliquots at -70°C. Note: Enzyme is very sensitive to freeze/thaw cycles.
| biological source | human |
| recombinant | expressed in baculovirus infected insect cells |
| assay | ≥80% (SDS-PAGE) |
| form | aqueous solution |
| mol wt | 71 kDa |
| packaging | pkg of 10 μg |
| concentration | >0.02 mg/mL |
| NCBI accession no. | NM_004412 |
| UniProt accession no. | Q6ICS7 |
| shipped in | dry ice |
| storage temp. | −70°C |
| Gene Information | human ... TRDMT1(1787) |
| 长度(mm) | |
| 宽度(mm) | |
| 高度(mm) | |
| 重量(kg) |
-
询价
-
询价
-
询价
-
¥ 2814.26
-
¥ 5887.85
-
询价
-
询价
-
询价
-
询价
-
询价
-
询价
-
询价
-
¥ 8135.09
-
询价
-
¥ 3372.68
-
瓶顶过滤器-500ml容量,MF75TM系列，聚苯乙烯外壳，75mmPES滤膜，孔径0.45um,适合瓶颈尺寸33mm，12/箱，295-3345，Nalgene，Thermofisher，赛默飞世尔¥ 1938.54
-
询价
-
¥ 1568.60
-
询价
-
¥ 2617.87
微信小程序
7X24小时在线咨询