Monoclonal Anti-DYNLL1, (N-terminal) antibody produced in mouse,100UG,SAB1402996-100UG,Sigma

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订货号 : 0BN0989
品牌型号 : Sigma SAB1402996-100UG
货期 : 询货期
最小订货量 : 1件
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  • 商品介绍
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产品介绍 Product Description

General description

Cytoplasmic dyneins are large enzyme complexes with a molecular mass of about 1,200 kD. They contain two force-producing heads formed primarily from dynein heavy chains, and stalks linking the heads to a basal domain, which contains a varying number of accessory intermediate chains. The complex is involved in intracellular transport and motility. The protein described in this record is a light chain and exists as part of this complex but also physically interacts with and inhibits the activity of neuronal nitric oxide synthase. Binding of this protein destabilizes the neuronal nitric oxide synthase dimer, a conformation necessary for activity, and it may regulate numerous biologic processes through its effects on nitric oxide synthase activity. Alternate transcriptional splice variants have been characterized. (provided by RefSeq)


Immunogen

DYNLL1 (NP_003737.1, 1 a.a. ~ 72 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Sequence
MCDRKAVIKNADMSEEMQQDSVECATQALEKYNIEKDIAAHIKKEFDKKYNPTWHCIVGRNFGSYVTHETKH


Physical form

Solution in phosphate buffered saline, pH 7.4


技术参数 Specifications
biological sourcemouse
Quality Level100
conjugateunconjugated
antibody formpurified immunoglobulin
antibody product typeprimary antibodies
clone1H7, monoclonal
formbuffered aqueous solution
mol wtantigen ~34.03 kDa
species reactivityhuman
technique(s)capture ELISA: suitable,immunofluorescence: suitable,indirect ELISA: suitable,western blot: 1-5 μg/mL
isotypeIgG2aκ
NCBI accession no.NM_003746
UniProt accession no.P63167
shipped indry ice
storage temp.−20°C
target post-translational modificationunmodified
Gene Informationhuman ... DYNLL1(8655)
长度(mm)
宽度(mm)
高度(mm)
重量(kg)
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