抗 CKMT1(长期) 兔抗,100UG,SAB1300100-100UG,Sigma

销售价: ¥ 3292.37 / 件
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订货号 : 0BM3142
品牌型号 : Sigma SAB1300100-100UG
货期 : 询货期
最小订货量 : 1件
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  • 商品介绍
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产品介绍 Product Description

General description

Mitochondrial creatine kinase (MtCK) is responsible for the transfer of high energy phosphate from mitochondria to the cytosolic carrier, creatine. It belongs to the creatine kinase isoenzyme family. It exists as two isoenzymes, sarcomeric MtCK and ubiquitous MtCK, encoded by separate genes. Mitochondrial creatine kinase occurs in two different oligomeric forms: dimers and octamers, in contrast to the exclusively dimeric cytosolic creatine kinase isoenzymes. Many malignant cancers with poor prognosis have shown overexpression of ubiquitous mitochondrial creatine kinase, this may be related to high energy turnover and failure to eliminate cancer cells via apoptosis. Ubiquitous mitochondrial creatine kinase has 80% homology with the coding exons of sarcomeric mitochondrial creatine kinase.


Immunogen

CKMT1 (60-94)
This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the N-terminal region of human CKMT1.


Physical form

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.


技术参数 Specifications
biological sourcerabbit
Quality Level200
conjugateunconjugated
antibody formIgG fraction of antiserum
antibody product typeprimary antibodies
clonepolyclonal
formbuffered aqueous solution
species reactivitymouse, human
technique(s)indirect ELISA: 1:1000,western blot: 1:100-1:500
NCBI accession no.NP_066270
UniProt accession no.P12532
shipped indry ice
storage temp.−20°C
target post-translational modificationunmodified
Gene Informationhuman ... CKMT1(1159)
长度(mm)
宽度(mm)
高度(mm)
重量(kg)
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