- 商品介绍
- 规格参数
- 包装参数
General description
A cell-permeable tetrabrominated cinnamic acid compound that acts as a potent and ATP-competitive inhibitor of Casein Kinase II (IC50 = 110 nM, Ki = 77 nM) with greater selectivity than TBB (Cat. Nos. 218697 and 218708) against a panel of 28 commonly studied kinases. Shown to efficiently induces apoptosis in Jurkat cells (DC50 = 7.7 µM). Also available as a 25 mM solution in DMSO (Cat. No. 218861).
Biochem/physiol Actions
Cell permeable: yes
Product competes with ATP.
Reversible: no
Target Ki: 77 nM against Casein Kinase II
Packaging
Packaged under inert gas
Other Notes
Pagano, M.A., et al. 2006. Chembiochem8, 129
Legal Information
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
Toxicity: Irritant (B)
| Quality Level | 100 |
| assay | ≥95% (HPLC) |
| form | solid |
| potency | 110 nM IC50 |
| manufacturer/tradename | Calbiochem® |
| storage condition | OK to freeze,protect from light |
| color | off-white |
| solubility | DMSO: 10 mg/mL (Use only fresh DMSO.),ethanol: 5 mg/mL |
| shipped in | ambient |
| storage temp. | 2-8°C |
| SMILES string | Brc1c(c(cc(c1Br)\C=C\C(=O)O)Br)Br |
| InChI | 1S/C9H4Br4O2/c10-5-3-4(1-2-6(14)15)7(11)9(13)8(5)12/h1-3H,(H,14,15)/b2-1+ |
| InChI key | SVJQCVOKYJWUBC-OWOJBTEDSA-N |
| 长度(mm) | |
| 宽度(mm) | |
| 高度(mm) | |
| 重量(kg) |
-
询价
-
¥ 1596.77
-
¥ 1563.36
-
询价
-
询价
-
询价
-
询价
-
询价
-
询价
-
询价
-
¥ 8520.40
-
¥ 9737.84
-
询价
-
询价
-
询价
-
¥ 6330.00
-
瓶顶过滤器-500ml容量,MF75TM系列，聚苯乙烯外壳，75mmSFCA滤膜，孔径0.2um,适合瓶颈尺寸45mm，12/箱，291-4520，Nalgene，Thermofisher，赛默飞世尔¥ 2856.42
-
¥ 1653.62
-
询价
-
¥ 8137.12
微信小程序
7X24小时在线咨询