Calpain-1 Substrate II, Fluorogenic,1MG,208772-1MGCN,Sigma

销售价: ¥ 2952.18 / 件
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订货号 0BW0849
品牌型号 Sigma 208772-1MGCN
货期 询货期
最小订货量 1件
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产品介绍 Product Description

General description

An internally quenched peptide substrate that is optimized for calpain-1 amino acid recognition motifs at the primed as well as the non-primed sides. Shown to be kinetically superior, in terms of turnover rate, to Calpain Substrate III, Fluorogenic (Cat. No. 208771), Calpain-1 Substrate, Fluorogenic (Cat. No. 208748), and Calpain Substrate II, Fluorogenic (Cat. No. 208731) by ~8-, 18-, and 310-fold, respectively. Excitation: ~335 nm; emission: ~505 nm.


Biochem/physiol Actions

Cell permeable: no
Primary Target
Calpain-1 Substrate
Product does not compete with ATP.
Reversible: no


Packaging

Packaged under inert gas


Physical form

Supplied as a trifluoroacetate salt.


Preparation Note

Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.


Other Notes

Cuerrier, D., et al. 2007. J. Biol. Chem.282, 9600.
Cuerrier, D., et al. 2005. J. Biol. Chem.280, 40632.
H₂N-Glu(EDANS)-Pro-Leu-Phe~Ala-Glu-Arg-Lys(DABCYL)-CO₂H


Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany


Disclaimer

Toxicity: Irritant (B)


技术参数 Specifications
Quality Segment100
assay≥97% (HPLC)
formlyophilized solid
manufacturer/tradenameCalbiochem®
storage conditionOK to freeze,desiccated (hygroscopic),protect from light
color red
solubilityDMSO: 5 mg/mL
fluorescenceλex ~505 nm,λem ~335 nm
shipped inwet ice
storage temp.−20°C
长度(mm)
宽度(mm)
高度(mm)
重量(kg)
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