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Antipain, Hydrochloride，5MG，178220-5MGCN，Sigma

销售价： ¥ 907.90 / 件

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订货号： 0BW0783

品牌型号： Sigma 178220-5MGCN

货期：询货期

最小订货量： 1件

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商品介绍
规格参数
包装参数

产品介绍 Product Description

General description

Effective concentration: 1-100 µM.
Peptidyl arginine aldehyde protease inhibitor produced by actinomycetes. Inhibitor of Ca²⁺-dependent endopeptidases. Has specificity similar to Leupeptin (Cat. No. 108975 ). Inhibits trypsin-like serine proteases, papain and some cysteine proteases (IC₅₀ = 300 µM).

Biochem/physiol Actions

Cell permeable: no
Primary Target
Trypsin-like serine proteases
Product does not compete with ATP.
Reversible: no
Target IC₅₀: 300 µM against trypsin-like serine proteases, papain and some cysteine proteases

Preparation Note

Following reconstitution, aliquot and freeze (-20°C) for long term storage or refrigerate (4°C) for short term storage. Stock solutions are stable for up to 1 week at 4°C or for up to 1 month at -20°C.

Other Notes

Lyupina, Y.V., et al. 1996. Eur. J. Pharmacol. 304, 23.
Umezawa, H. 1976. Methods Enzymol.55, 678.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Toxicity: Standard Handling (A)

技术参数 Specifications

Quality Segment	100
description	RTECS - YV9350800
form	solid
manufacturer/tradename	Calbiochem^®
storage condition	OK to freeze,desiccated (hygroscopic)
color	white to slightly yellowish
solubility	water: 10 mg/mL
shipped in	ambient
storage temp.	2-8°C
SMILES string	[Cl-].[Cl-].N([C@@H](C(C)C)C(=O)NC(=O)[C@@H](NC(=O)NC(Cc1ccccc1)C(=O)O)CCCN=C(N)N)C(CCCN=C(N)N)C=O.[H+].[H+]
InChI	1S/C27H44N10O6.2ClH/c1-16(2)21(34-18(15-38)10-6-12-32-25(28)29)23(40)37-22(39)19(11-7-13-33-26(30)31)35-27(43)36-20(24(41)42)14-17-8-4-3-5-9-17;;/h3-5,8-9,15-16,18-21,34H,6-7,10-14H2,1-2H3,(H,41,42)(H4,28,29,32)(H4,30,31,33)(H2,35,36,43)(H,37,39,40);2*1H/t18?,19-,20?,21-;;/m0../s1
InChI key	GXQPAKIVOCLCHD-BXLPLHKWSA-N

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