- 商品介绍
- 规格参数
- 包装参数
General description
A cell-permeable, selective, reversible, and non-competitive allosteric inhibitor of PTP1B (IC50 = 4 µM and 8 µM for PTP1B403 and PTP1B298, respectively). Binds to a novel site away from the catalytic pocket and inhibits PTP1B activity by preventing closure of the WPD loop.
Biochem/physiol Actions
Cell permeable: yes
IC50 = 4 and 8 µM for PTP1B403 and PTP1B298, respectively
Reversible: yes
Packaging
Packaged under inert gas
Physical form
A 10 mM (2 mg/270 µl) solution of PTP1B Inhibitor (Cat. No. 539741) in DMSO.
Preparation Note
Following initial thaw, aliquot and freeze (-20°C).
Other Notes
Wiesmann, C., et al. 2004. Nat. Struct. Mol. Biol.11, 730.
Legal Information
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
Toxicity: Irritant (B)
| Quality Level | 100 |
| assay | ≥97% (HPLC) |
| form | liquid |
| manufacturer/tradename | Calbiochem® |
| storage condition | OK to freeze,avoid repeated freeze/thaw cycles,desiccated (hygroscopic),protect from light |
| shipped in | ambient |
| storage temp. | −20°C |
| 长度(mm) | |
| 宽度(mm) | |
| 高度(mm) | |
| 重量(kg) |
-
¥ 1148.92
-
询价
-
¥ 1683.78
-
¥ 1259.40
-
询价
-
询价
-
¥ 1302.89
-
¥ 1779.22
-
¥ 1451.54
-
询价
-
询价
-
询价
-
询价
-
询价
-
询价
-
¥ 4390.38
-
¥ 2617.87
-
¥ 2617.87
-
¥ 4020.77
-
¥ 3404.94
微信小程序
7X24小时在线咨询