- 商品介绍
- 规格参数
- 包装参数
General description
Cell-permeable cGMP analog that is more resistant to phosphodiesterases than cGMP. Preferentially activates protein kinase G. Inhibits thrombin-stimulated arachidonic acid release in human platelets.
Biochem/physiol Actions
Cell permeable: yes
Primary Target
protein kinase G
Product does not compete with ATP.
Reversible: no
Packaging
Packaged under inert gas
Preparation Note
Following reconstitution, aliquot and freeze (-20°C). Aqueous stock solutions are stable for up to 1 week at -20°C.
Other Notes
Kwak, B.R., and Jongsma, H.J. 1996. Mol. Cell. Biochem. 157, 93.
Perreault, T., and DeMarte, J. 1993. Am. J. Physiol. 264, H302.
Ruth, P., et al. 1991. Eur. J. Biochem.202, 1339.
Schwarzschild, M.A., and Zigmond, R.E. 1991. J. Neurochem.56, 400.
Legal Information
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
Toxicity: Standard Handling (A)
| Quality Level | 100 |
| assay | ≥98% (HPLC) |
| form | solid |
| manufacturer/tradename | Calbiochem® |
| storage condition | OK to freeze,desiccated |
| color | white |
| solubility | water: 200 mg/mL |
| shipped in | ambient |
| storage temp. | −20°C |
| SMILES string | [P]1(=O)(O[C@@H]2[C@H](O[C@H]([C@@H]2O)[n]3c4[nH]c(n[c](c4nc3Br)=O)N)CO1)O |
| InChI | 1S/C10H11BrN5O7P/c11-9-13-3-6(14-10(12)15-7(3)18)16(9)8-4(17)5-2(22-8)1-21-24(19,20)23-5/h2,4-5,8,17H,1H2,(H,19,20)(H3,12,14,15,18)/t2-,4-,5-,8-/m1/s1 |
| InChI key | YUFCOOWNNHGGOD-UMMCILCDSA-N |
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