Anti-BCAR3 Antibody,100UG,ABT336,Sigma

销售价: ¥ 3419.24 / 件
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订货号 0BV8569
品牌型号 Sigma ABT336
货期 询货期
最小订货量 1件
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产品介绍 Product Description

General description

Breast cancer anti-estrogen resistance protein 3 (BCAR3), also known as Novel SH2-containing protein 2 (NSP2) and SH2 domain-containing protein 3B (SH2D3B) is an adapter protein that regulates the proliferation in breast cancer cells. BCAR3 may also be regulated by cellular adhesion to extracellular matrix proteins. BCAR3 is found in several cancer cell lines; however, it is not found in nonmalignant breast tissue. When BCAR3 is overexpressed, it confers anti-estrogen resistance in breast cancer cell lines.
~104 kDa observed


Immunogen

KLH-conjugated linear peptide corresponding to human BCAR3.


Application

Anti-BCAR3 Antibody is a highly specific rabbit polyclonal antibody, that targets Breast cancer Anti-estrogen resistance protein 3 & has been tested in western blotting.
Research Category
Apoptosis & Cancer


Physical form

Antigen Affinity Purified
Purified rabbit polyclonal in buffer containing PBS with up to 0.1% sodium azide.


Preparation Note

Stable for 1 year at 2-8°C from date of receipt.


Analysis Note

Control
Mouse kidney tissue lysate
Evaluated by Western Blotting in mouse kidney tissue lysate.

Western Blotting Analysis: 1 µg/mL of this antibody detected BCAR3 in 15 µg of mouse kidney tissue lysate.


Other Notes

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.


Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.


技术参数 Specifications
biological sourcerabbit
Quality Segment100
conjugateunconjugated
antibody formaffinity isolated antibody
antibody product typeprimary antibodies
clonepolyclonal
purified byaffinity chromatography
species reactivitymouse
species reactivity (predicted by homology)human (immunogen homology)
technique(s)western blot: suitable
UniProt accession no.O75815
shipped inwet ice
target post-translational modificationunmodified
Gene Informationhuman ... BCAR3(8412)
长度(mm)
宽度(mm)
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