- 商品介绍
- 规格参数
- 包装参数
General description
Observed molecular weight, 73 kDa
Note this protein can be highly modified and several isoforms exist.
TACC2, also known as transforming acidic coiled-coil-containing protein 2, belongs to the transforming acidic coiled-coil-containing (TACC) protein family. This group of proteins is defined by its highly conserved coiled-coil domain. This domain is necessary for the assignment of the centrosome-spindle apparatus during cell cycling. There are three proteins belonging to the TACC family; TACC1, TACC2, and TACC3. TACC2 has been reported as playing a necessary role in cultured cell microtubule stabilization. It has also been shown that the binding of TACC2 by T antigen can cause chromosomal instability and mitotic defects (Tei, 2009). Research into the over expression of TACC2 strongly suggests a potential function as a tumor suppressor (Tei, 2009).
Immunogen
KLH-conjugated linear peptide corresponding to the mature chain of mouse TACC2.
Application
Anti-TACC2 Antibody is a Rabbit Polyclonal Antibody for detection of TACC2 also known as transforming acidic coiled-coil containing protein 2 & has been validated in WB.
Analysis Note
Evaluated by Western Blot in mouse testis tissue lysate.
Western Blot Analysis: 2 µg/mL of this antibody detected TACC2 on 10 µg of mouse testis tissue lysate.
Other Notes
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
Legal Information
UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany
| biological source | rabbit |
| Quality Segment | 100 |
| conjugate | unconjugated |
| antibody form | affinity isolated antibody |
| antibody product type | primary antibodies |
| clone | polyclonal |
| purified by | affinity chromatography |
| species reactivity | human, mouse |
| species reactivity (predicted by homology) | rat (based on 100% sequence homology) |
| manufacturer/tradename | Upstate® |
| technique(s) | western blot: suitable |
| NCBI accession no. | NP_996738 |
| UniProt accession no. | Q9JJG0 |
| shipped in | wet ice |
| target post-translational modification | unmodified |
| Gene Information | human ... TACC2(10579) |
| 长度(mm) | |
| 宽度(mm) | |
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| 重量(kg) |
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