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- 规格参数
- 包装参数
General description
MT1-MMP plays an important role during endothelial cell migration and matrix remodeling. Although the role of MT1-MMP in endothelial cell motility is not fully characterized, its activity appears to modulate endothelial migration, invasion, and formation of capillary tubes during the angiogenic response (Galvez, 2001). MT1-MMP also appears to play a key role in monocyte revruitment during inflammation.
Application
Anti-MMP-14 Antibody, catalytic domain, clone LEM-2/63.1 detects level of MMP-14 & has been published & validated for use in ELISA, IP & WB.
Western Blot
Immunohistochemistry: Frozen sections
Immunofluorescence
Immunoprecipitation
Flow Cytometry
Blocking
Optimal working dilutions must be determined by the end user.
Biochem/physiol Actions
LEM-2/63.1 reacts with human MT1-MMP and displays crossreactivity with mouse specimens. This antibody was generated against the catalytic domain of MT1-MMP and is able to inhibit enzyme activity.
Physical form
Format: Purified
Other Notes
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
Legal Information
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
| biological source | mouse |
| Quality Segment | 100 |
| conjugate | unconjugated |
| antibody form | purified immunoglobulin |
| antibody product type | primary antibodies |
| clone | LEM-2/63.1, monoclonal |
| species reactivity | mouse |
| manufacturer/tradename | Chemicon® |
| technique(s) | ELISA: suitable,immunoprecipitation (IP): suitable,western blot: suitable |
| NCBI accession no. | NM_004995.2 |
| UniProt accession no. | P50281 |
| shipped in | wet ice |
| target post-translational modification | unmodified |
| Gene Information | human ... MMP14(4323) |
| 长度(mm) | |
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