Anti-NIPSNAP Antibody,100UG,ABN343,Sigma

销售价: ¥ 3875.14 / 件
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订货号 : 0BV6510
品牌型号 : Sigma ABN343
货期 : 询货期
最小订货量 : 1件
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产品介绍 Product Description

General description

NIPSNAP is a member of an evolutionarily well conserved gene family and has a strong sequence similarity to the central portion of a protein encoded by C. elegans chromosome III between a 4-nitrophenylphosphatase (NIP) domain and non-neuronal SNAP25-like protein. Recent studies have indicated that NIPSNAP is involved in the regulation of the Ca2+-selective transient receptor potential vanilloid channel 6 (TRPV6). NIPSNAP1 associates with TRPV6 at the plasma membrane and inhibits TRPV6 currents. Other studies show that NIPSNAP’s expression is reduced in the phenylketonuria (PKU) brain, suggesting that NIPSNAP may play a role in memory.
~33 kDa observed


Immunogen

KLH-conjugated linear peptide corresponding to human NIPSNAP.


Application

Detect the NIPSNAP protein using this Anti-NIPSNAP validated for use in WB & IHC.
Immunohistochemistry Analysis: 2.5 µg/mL of this antibody from a representative lot detected NIPSNAP in human brain tissue.


Analysis Note

Evaluated by Western Blot in human brain tissue lysate.

Western Bloting Analysis: 1 µg/mL of this antibody detected NIPSNAP in 15 µg of human brain tissue lysate.


Other Notes

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.


技术参数 Specifications
biological sourcerabbit
Quality Segment100
conjugateunconjugated
antibody formaffinity isolated antibody
antibody product typeprimary antibodies
clonepolyclonal
purified byaffinity chromatography
species reactivityhuman
technique(s)immunohistochemistry: suitable,western blot: suitable
UniProt accession no.Q9BPW8
shipped inwet ice
target post-translational modificationunmodified
Gene Informationhuman ... NIPSNAP1(8508)
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高度(mm)
重量(kg)
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