Anti-Integrin β3 Antibody, clone B3A, azide free，100UG，MAB2023Z，Sigma 供应商、价格、厂家、报价、规格参数

产品介绍 Product Description

General description

110 kDa

Immunogen

Human integrin alphaVbeta3 heterodimer isolated from placenta.

Application

Anti-Integrin β3 Antibody, clone B3A, azide free detects level of Integrin β3 & has been published & validated for use in FC, FUNC & WB.
Flow cytometry

Function-blocking of integrin beta3-mediated adhesion to ECM proteins.

Western blot (reducing conditions) Optimal working dilutions must be determined by end user.
Research Category
Cell Structure
Research Sub Category
Integrins

Biochem/physiol Actions

Specific for human integrin beta 3 (other species not tested).

Physical form

Format: Purified
Protein A Purified mouse immunoglobulin in 20 mM sodium phosphate, 250 mM NaCl, pH. 7.6, with no preservatives.
Protein A purified

Preparation Note

Maintain for 1 year at 2–8°C from date of shipment. Aliquot to avoid repeated freezing and thawing. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Analysis Note

Control
Positive Control: U251 or D54 human cell lines. Membrane preps are recommended for western blots.
Human endothelium cells (expression of integrin alpha V beta 3 may need to be upregulated by phorbol esters stimulation). Skin (Basement Membrane)

Other Notes

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Legal Information

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

技术参数 Specifications

biological source	mouse
Quality Segment	100
antibody form	purified immunoglobulin
antibody product type	primary antibodies
clone	B3A, monoclonal
species reactivity	human
manufacturer/tradename	Chemicon^®
technique(s)	flow cytometry: suitable,western blot: suitable
NCBI accession no.	NM_000212.2
UniProt accession no.	P05106
shipped in	wet ice
target post-translational modification	unmodified
Gene Information	human ... ITGB3(3690)

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