Anti-Phospho-PKC zeta-T560 antibody produced in rabbit,100UL,SAB5701912-100UL,Sigma

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订货号 0BV1462
品牌型号 Sigma SAB5701912-100UL
货期 询货期
最小订货量 1件
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产品介绍 Product Description

General description

Protein kinase C (PKC) zeta is a member of the PKC family of serine/threonine kinases which are involved in a variety of cellular processes such as proliferation, differentiation and secretion. Unlike the classical PKC isoenzymes which are calcium-dependent, PKC zeta exhibits a kinase activity which is independent of calcium and diacylglycerol but not of phosphatidylserine. Furthermore, it is insensitive to typical PKC inhibitors and cannot be activated by phorbol ester. Unlike the classical PKC isoenzymes, it has only a single zinc finger module. These structural and biochemical properties indicate that the zeta subspecies is related to, but distinct from other isoenzymes of PKC. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]


Immunogen

A phospho specific peptide corresponding to residues surrounding T560 of human PKC zeta


Physical form

Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.


技术参数 Specifications
biological sourcerabbit
Quality Segment100
antibody product typeprimary antibodies
clonemonoclonal
formliquid
species reactivityhuman
concentration1.05 mg/mL
technique(s)western blot: 1:500-1:2000
UniProt accession no.Q05513
shipped inwet ice
storage temp.−20°C
target post-translational modificationphosphorylation (pThr560)
Gene Informationhuman ... PRKCZ(5590)
长度(mm)
宽度(mm)
高度(mm)
重量(kg)
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