Monoclonal Anti-Brain-derived Neurotrophic Factor antibody produced in mouse,0.5MG,B5050-.5MG,Sigma

销售价: ¥ 8092.02 / 件
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订货号 0BU5412
品牌型号 Sigma B5050-.5MG
货期 询货期
最小订货量 1件
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产品介绍 Product Description

General description

The antibody shows ~5% cross-reactivity with recombinant human β−NGF and recombinant rat β−NGF.


Immunogen

Recombinant human BDNF, expressed in Sf 21 cells.


Application

Applications in which this antibody has been used successfully, and the associated peer-reviewed papers, are given below.
Immunofluorescence (1 paper)


Biochem/physiol Actions

Brain derived neurotrophic factor (BDNF) belongs to a family of secreted proteins called neurotrophins that includes, nerve growth factor (NGF), neurotrophin-3 (NT3) and NT4/5. BDNF is expressed in the developing and the mature brain. The downstream pathways promoted by BDNF include PI3K, MAPK and JAK/STAT. The most important role of BDNF is the regulation of synaptic transmission and plasticity, protein synthesis and phosphorylation of local proteins.


Physical form

Lyophilized from a 0.2 μm filtered solution in phosphate buffered saline containing carbohydrates.


Preparation Note

Purified from ascites fluid using protein A.


Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.


技术参数 Specifications
biological sourcemouse
Quality Segment100
conjugateunconjugated
antibody formpurified immunoglobulin
antibody product typeprimary antibodies
clone35928.11, monoclonal
formlyophilized powder
species reactivityhuman
technique(s)immunohistochemistry (formalin-fixed, paraffin-embedded sections): 8-25 μg/mL using human spinal cord,western blot: 1-2 μg/mL
isotypeIgG1
UniProt accession no.P23560
storage temp.−20°C
target post-translational modificationunmodified
Gene Informationhuman ... BDNF(627)
长度(mm)
宽度(mm)
高度(mm)
重量(kg)
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