Arginine Splicing Factor, His tagged human,5UG,SRP2104-5UG,Sigma

销售价: ¥ 5627.66 / 件
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订货号 : 0BT9837
品牌型号 : Sigma SRP2104-5UG
货期 : 询货期
最小订货量 : 1件
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产品介绍 Product Description

Biochem/physiol Actions

ASF also known as SF2 is a member of the SR protein family. It is an essential pre-mRNA splicing factor required for both single and alternative splicing. Phosphorylation on serine residues located within the SR domain directly regulates ASF/SF2 activity and compartmentalization of other SR splicing factors. In addition to interacting with RNA and other splicing factors, such as U1-70K, U2AF and other SR proteins, ASF/SF2 also directly or indirectly interacts with HIV regulatory protein Rev, the C-terminal domain (CTD) of the largest subunit of RNA polymerase II, and numerous transcription factors, thereby suggesting a potential role of ASF/SF2 in coordinating transcription and pre-mRNA splicing.


Physical form

Clear and colorless frozen liquid solution


Preparation Note

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. While working, please keep sample on ice.


技术参数 Specifications
biological sourcehuman
recombinantexpressed in insect cells
assay≥85% (SDS-PAGE)
formfrozen liquid
mol wt ~29.3 kDa
packagingpkg of 5 μg
storage conditionavoid repeated freeze/thaw cycles
concentration350 μg/mL
color clear, colorless
NCBI accession no.NM_006924
UniProt accession no.Q07955
shipped indry ice
storage temp.−70°C
Gene Informationhuman ... SRSF1(6426)
长度(mm)
宽度(mm)
高度(mm)
重量(kg)
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