β-雌二醇17-(β-ᴅ-葡萄糖醛酸) 钠盐,10MG,E1127-10MG,Sigma

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订货号 0BT6160
品牌型号 Sigma E1127-10MG
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最小订货量 1件
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产品介绍 Product Description

Application

β-Estradiol 17-(β-D-glucuronide) sodium salt has been used as a standard to determine the quantity of β-Estradiol 17-(β-D-glucuronide) during UDP-glucuronosyltransferase assay. It has also been used as a constituent of modified synthetic oviduct fluid (m-SOF) for maturation of bovine cumulus oocyte complexes (COC).


Biochem/physiol Actions

Estradiol 17-(β-D-glucuronide) (E217G) is a naturally occurring conjugated estrogen. It is formed in the liver and later excreted in bile. Increased concentrations of E217G leads to the development of cholestasis during the later stages of pregnancy, a condition which occurs with high frequency in the Dubin-Johnson syndrome.


Features and Benefits

This compound is a featured product for ADME Tox research. Click here to discover more featured ADME Tox products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.


技术参数 Specifications
sterilitynon-sterile
Quality Segment200
assay≥98% (HPLC)
formpowder
solubility0.1 M NaOH: 10 mg/mL, clear to slightly hazy, colorless to faintly yellow
shipped inambient
storage temp.−20°C
SMILES string[Na].CC12CCC3C(CCc4cc(O)ccc34)C1CCC2OC5OC(C(O)C(O)C5O)C(O)=O
InChI1S/C24H32O8.Na.H/c1-24-9-8-14-13-5-3-12(25)10-11(13)2-4-15(14)16(24)6-7-17(24)31-23-20(28)18(26)19(27)21(32-23)22(29)30;;/h3,5,10,14-21,23,25-28H,2,4,6-9H2,1H3,(H,29,30);;
InChI keyGPLPNZUTAJWRLU-UHFFFAOYSA-N
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