Monoclonal Anti-SLC27A2 antibody produced in mouse,100UG,SAB1403096-100UG,Sigma

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订货号 0BT4993
品牌型号 Sigma SAB1403096-100UG
货期 询货期
最小订货量 1件
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产品介绍 Product Description

General description

The protein encoded by this gene is an isozyme of long-chain fatty-acid-coenzyme A ligase family. Although differing in substrate specificity, subcellular localization, and tissue distribution, all isozymes of this family convert free long-chain fatty acids into fatty acyl-CoA esters, and thereby play a key role in lipid biosynthesis and fatty acid degradation. This isozyme activates long-chain, branched-chain and very-long-chain fatty acids containing 22 or more carbons to their CoA derivatives. It is expressed primarily in liver and kidney, and is present in both endoplasmic reticulum and peroxisomes, but not in mitochondria. Its decreased peroxisomal enzyme activity is in part responsible for the biochemical pathology in X-linked adrenoleukodystrophy. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. (provided by RefSeq)


Immunogen

SLC27A2 (NP_003636, 25 a.a. ~ 123 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Sequence
YFFQDIGYFLKVAAVGRRVRSYGQRRPARTILRAFLEKARQTPHKPFLLFRDETLTYAQVDRRSNQVARALHDHLGLRQGDCVALLMGNEPAYVWLWLG


Biochem/physiol Actions

Solute carrier family 27 member 2 (SLC27A2) has a role in fatty acid transport. It also mediates the activation of fatty acids having a chain length of 22 or more carbons.


Physical form

Solution in phosphate buffered saline, pH 7.4


技术参数 Specifications
biological sourcemouse
Quality Segment100
conjugateunconjugated
antibody formpurified immunoglobulin
antibody product typeprimary antibodies
clone1F1, monoclonal
formbuffered aqueous solution
mol wtantigen ~37 kDa
species reactivityhuman
technique(s)capture ELISA: suitable,immunofluorescence: suitable,indirect ELISA: suitable
isotypeIgG2aκ
NCBI accession no.NM_003645
UniProt accession no.O14975
shipped indry ice
storage temp.−20°C
target post-translational modificationunmodified
Gene Informationhuman ... SLC27A2(11001)
长度(mm)
宽度(mm)
高度(mm)
重量(kg)
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