Anti-HDAC6 antibody produced in rabbit，100UG，SAB4500011-100UG，Sigma 供应商、价格、厂家、报价、规格参数

产品介绍 Product Description

General description

Histone deacetylase 6 (HDAC6) is a class IIb histone deacetylase which is localized in the cytosol. It has two catalytic domains. The protein is expressed in the heart, brain, colon, breast, ovary, pancreas and prostate glands. The gene encoding HDAC6 is localized on human chromosome Xp11.23. Anti-HDAC6 Antibody detects endogenous levels of total HDAC6 protein.

Immunogen

The antiserum was produced against synthesized peptide derived from human HDAC6.

Immunogen Range: 7-56

Biochem/physiol Actions

Histone deacetylase 6 (HDAC6) deacetylates substrates like α-tubulin. It is involved in endocytosis and autophagy. HDAC6 functions in cellular mechanisms connected to cancer and modulates cell motility.

Features and Benefits

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Physical form

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

技术参数 Specifications

biological source	rabbit
Quality Segment	100
conjugate	unconjugated
antibody form	affinity isolated antibody
antibody product type	primary antibodies
clone	polyclonal
form	buffered aqueous solution
mol wt	antigen 131 kDa
species reactivity	human, mouse
concentration	~1 mg/mL
technique(s)	ELISA: 1:1000,immunofluorescence: 1:100-1:500,immunohistochemistry: 1:50-1:100,western blot: 1:500-1:1000
NCBI accession no.	Q9UBN7
UniProt accession no.	Q9UBN7
shipped in	wet ice
storage temp.	−20°C
target post-translational modification	unmodified
Gene Information	human ... HDAC6(10013)

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