Monoclonal Anti-α₁-Acid Glycoprotein antibody produced in mouse,0.2ML,A5566-.2ML,Sigma

销售价: ¥ 2326.32 / 件
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订货号 0BS4976
品牌型号 Sigma A5566-.2ML
货期 询货期
最小订货量 1件
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产品介绍 Product Description

General description

Monoclonal Anti-α1-Acid Glycoprotein (mouse IgG1 isotype) is derived from the AGP-47 hybridoma produced by the fusion of mouse myeloma cells and splenocytes from BALB/c mice. α1-Acid Glycoprotein (AGP) is an acute-phase plasma protein. This protein is mainly produced in the hepatocytes. AGP1 gene is mapped on the human chromosome at 9q32.


Immunogen

human α1-acid glycoprotein (AGP).


Biochem/physiol Actions

α1-Acid Glycoprotein (AGP) associates with haptoglobin and C-reactive protein, which indicates inflammation. Higher levels of AGP is associated with various inflammatory diseases, trauma, malignancies, myocardial infarction, rheumatoid arthritis, after major surgery, and in cases of chronic pain. This protein is capable of binding and transporting basic and neutral drugs.
Recognizes an epitope located on the 44 kDa subunit of denatured-reduced AGP using the immunoblotting technique. It does not cross react with human serum amyloid P component, human haptoglobin, human C-reactive protein, and human IgG.


Physical form

The product is provided as ascites fluid with 0.1% sodium azide as a preservative.


Preparation Note

For continuous use, store at 2-8 °C for up to one month. For extended storage, the solution may be frozen in working aliquots. Repeated freezing and thawing is not recommended. Storage in "frost-free" freezers is not recommended. If slight turbidity occurs upon prolonged storage, clarify the solution by centrifugation before use.


Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.


技术参数 Specifications
biological sourcemouse
Quality Segment200
conjugateunconjugated
antibody formascites fluid
antibody product typeprimary antibodies
cloneAGP-47, monoclonal
contains15 mM sodium azide
species reactivityhuman, baboon (weakly)
should not react with canine, bovine
technique(s)dot blot: suitable,indirect ELISA: suitable,western blot: 1:10,000
isotypeIgG1
UniProt accession no.P02763
shipped indry ice
storage temp.−20°C
target post-translational modificationunmodified
Gene Informationhuman ... ORM1(5004)
长度(mm)
宽度(mm)
高度(mm)
重量(kg)
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