- 商品介绍
- 规格参数
- 包装参数
Biochem/physiol Actions
RO5256390 is an agonist of Trace amine-associated receptor 1 (TAAR1), a GPCR primarily found in the brain, expressed in areas where the major monoamine amine transmitters (DA and NE) are also present. RO5256390 is a selective TAAR1 agonist shown to be a negative regulator of dopamine transmission. It has antipsychotic activity in models of schizophrenia, reduces cocaine′s reinforcng effects, and blocks binge-eating disorder.
TAAR1 agonist
| Quality Level | 100 |
| assay | ≥98% (HPLC) |
| form | powder |
| optical activity | [α]/D 14 to 19°, c = 1 in methanol |
| color | white to beige |
| solubility | DMSO: 10 mg/mL, clear |
| storage temp. | 2-8°C |
| SMILES string | CC[C@@H](C[C@H]1COC(N)=N1)C2=CC=CC=C2 |
| InChI | 1S/C13H18N2O/c1-2-10(11-6-4-3-5-7-11)8-12-9-16-13(14)15-12/h3-7,10,12H,2,8-9H2,1H3,(H2,14,15)/t10-,12-/m0/s1 |
| InChI key | IXDKFUBXESWHSL-JQWIXIFHSA-N |
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