- 商品介绍
- 规格参数
- 包装参数
General description
The protein encoded by this gene is the CD3-epsilon polypeptide, which together with CD3-gamma, -delta and -zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T-cell receptor-CD3 complex. This complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. The genes encoding the epsilon, gamma and delta polypeptides are located in the same cluster on chromosome 11. The epsilon polypeptide plays an essential role in T-cell development. Defects in this gene cause immunodeficiency. This gene has also been linked to a susceptibility to type I diabetes in women. The protein encoded by this gene is the CD3-gamma polypeptide, which together with CD3-epsilon, -delta and -zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T-cell receptor-CD3 complex. This complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. The genes encoding the epsilon, gamma and delta polypeptides are located in the same cluster on chromosome 11. Defects in this gene are associated with T cell immunodeficiency.
Immunogen
PBS with 0.05% proclin300,0.05% BSA,50% glycerol,pH7.3.
Recombinant fusion protein containing a sequence corresponding to amino acids 1-207(CD3E)& 1-375(CD3G) of human CD3 epsilon&CD3 gamma Heterodimer.
Application
WB, FC
| biological source | rabbit |
| Quality Level | 100 |
| conjugate | unconjugated |
| material | colorless |
| clone | 4F5G4, monoclonal |
| form | liquid |
| mol wt | 23 kDa |
| species reactivity | human |
| concentration | 0.43 mg/mL |
| technique(s) | flow cytometry: 1:50 - 1:200,western blot: 1:500 - 1:2000 |
| color | colorless |
| isotype | IgG |
| UniProt accession no. | P07766,P09693 |
| shipped in | wet ice |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| Gene Information | human ... CD3(epsilon+gamma) |
| 长度(mm) | |
| 宽度(mm) | |
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| 重量(kg) |
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¥ 4164.19
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¥ 2019.57
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¥ 1866.29
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¥ 8520.40
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¥ 8982.64
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¥ 4020.77
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¥ 1351.48
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¥ 2288.54
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¥ 56581.65
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¥ 145427.01
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