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Biochem/physiol Actions
The 21-residue peptide MOG 35-55 contains an antigenic epitope responsible for the activation of CD8 encephalitogenic T cells in mice. Two truncated peptides, MOG 40-54 and MOG 44-54 were shown to bind the recombinant H-2Db protein. This complex then binds MOG specific CD8 T cells. While MOG 40-54 retained the full capability of inducing paralytic disease, MOG 44-54 only partialy causes clinical paralysis and central nervous system inflamation.
Physical form
Lyophilized from 0.1% aqueous TFA.
Other Notes
Lyophilized from 0.1% TFA in H2O
| form | lyophilized powder |
| Quality Segment | 200 |
| color | white |
| solubility | deionized water: soluble |
| UniProt accession no. | Q61885,Q63345 |
| storage temp. | −20°C |
| Gene Information | mouse ... Mog(17441) rat ... Mog(24558) |
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