- 商品介绍
- 规格参数
- 包装参数
产品介绍
Product Description
Biochem/physiol Actions
RWJ 67657 is an orally active, potent and selective inhibitor of p38α and p38β MAP kinases. RWJ 67657 inhibits the release of TNF-α and IL-1β from LPS induced blood mononuclear cells. It exhibits cardioprotective and anti-inflammatory activities in vivo.
orally active, potent and selective inhibitor of p38α and p38β MAP kinases
技术参数
Specifications
| assay | ≥98% (HPLC) |
| form | powder |
| color | white to beige |
| solubility | DMSO: 2 mg/mL, clear |
| web metadata keyword.default | RWJ 67657 4-(4-Fluorophenyl)-1-(3-Phenylpropyl)-imidazole,RWJ 67657 CAS 215303-72-3,RWJ 67657 TNF-α IL-1β release inhibitor,RWJ 67657 anti-inflammatory agent for research,RWJ 67657 cardioprotective compound,RWJ 67657 for laboratory use,RWJ 67657 inhibitor p38 MAP kinase,RWJ 67657 p38 MAP kinase selective inhibitor,RWJ 67657 p38α p38β inhibitor,Sigma-Aldrich RWJ 67657 MAP kinase inhibitor,high purity RWJ 67657 for scientific research,p38 MAPK inhibitor RWJ 67657 in vivo studies,p38 MAPK inhibitor for inflammatory disease studies,research grade RWJ 67657 inhibitor |
| storage temp. | 2-8°C |
| SMILES string | OCCC#CC1=NC(C2=CC=C(F)C=C2)=C(C3=CC=NC=C3)N1CCCC4=CC=CC=C4 |
| InChI | 1S/C27H24FN3O/c28-24-13-11-22(12-14-24)26-27(23-15-17-29-18-16-23)31(25(30-26)10-4-5-20-32)19-6-9-21-7-2-1-3-8-21/h1-3,7-8,11-18,32H,5-6,9,19-20H2 |
| InChI key | QSUSKMBNZQHHPA-UHFFFAOYSA-N |
| 长度(mm) | |
| 宽度(mm) | |
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| 重量(kg) |
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