- 商品介绍
- 规格参数
- 包装参数
General description
Spexin is a 4-amino acidpeptide, produced by neurons in the hypothalamus.
Application
Spexin for its potential roles in regulating appetite and metabolism,influencing reproductive hormones, in metabolic and endocrine research.
Biochem/physiol Actions
Spexin 1 (SPX) is a 14-aa amidated peptide that acts as an endogenousgalanin receptor GAL2/3 agonist (EC50 = 161 nM/GAL2, 626 nM/GAL3, >10µM/GAL1 by reporter assays using respective HEK293 transfectants) that inhibits facilitated fatty acid (FA) uptake in diet-induced obesity (DIO) mouse adipocytes cultures (0.1-1 ng/mL) and induces rat stomach muscle contraction ex vivo (EC50 = 750 nM). SPX reduces caloric intake in rats (∼32%; 35 µg/kg/day s.c.) with corresponding weight loss and significantly reduces the RER at night as well as increases locomotion in mice in vivo (25 µg/kg/day i.p.). Note: peptide sequence is conserved in human, murine, rat and many other mammalian species.
Disclaimer
Hygroscopic Store with desiccant
| Quality Segment | 100 |
| assay | ≥95% (HPLC) |
| form | (Powder or Lyophilized powder or film) |
| storage condition | desiccated |
| color | white to off-white |
| storage temp. | -10 to -25°C |
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瓶顶过滤器-500ml容量,MF75TM系列，聚苯乙烯外壳，75mmPES滤膜，孔径0.45um,适合瓶颈尺寸33mm，12/箱，295-3345，Nalgene，Thermofisher，赛默飞世尔¥ 1938.54
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NALGENE 180透明塑料管，透明，柔软，多用，经济，内径 x 外径x壁厚，1/8 x 1/4 x 1/16，英寸，每箱数量50，50/箱，8000-0020，Thermofisher，赛默飞世尔询价
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