- 商品介绍
- 规格参数
- 包装参数
General description
hnRNP-A1 (heterogeneous nuclear ribonucleoprotein) is a pre-mRNA/mRNA binding protein, that belongs to the hnRNP family. It is located in chromosome 12q13.1. It is located in the nucleoplasm but it travels between the nucleus and the cytoplasm. It has two RNP motif RNA-binding domains (RBDs) at the amino terminus and a glycine-rich domain at the carboxyl terminus.
Immunogen
purified human hnRNP-A1.
Application
Anti-hnRNP-A1 has been used in immunofluorescence, immunohistochemistry and western blotting.
Does not immunoprecipitate the hnRNP complex.
Biochem/physiol Actions
hnRNP-A1 (heterogeneous nuclear ribonucleoprotein) participates in several RNA metabolisms. It also participates in deep vein thrombosis patients with behçet′s disease. hnRNPA1 mutations results in amyotrophic lateral sclerosis and multisystem proteinopathy.
Physical form
Solution in 0.01 M phosphate buffered saline, pH 7.4, and 15 mM sodium azide.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
| biological source | mouse |
| Quality Level | 200 |
| conjugate | unconjugated |
| antibody form | purified immunoglobulin |
| antibody product type | primary antibodies |
| clone | 9H10, monoclonal |
| form | buffered aqueous solution |
| mol wt | antigen ~34 kDa |
| species reactivity | human, hamster, monkey, rat, bovine, mouse, canine |
| technique(s) | immunocytochemistry: suitable,immunohistochemistry: suitable,immunoprecipitation (IP): suitable,microarray: suitable,western blot: 0.5-1.0 μg/mL using total cell extract of 293T cells |
| isotype | IgG2b |
| UniProt accession no. | P09651 |
| shipped in | dry ice |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| Gene Information | human ... HNRNPA1(3178) mouse ... Hnrnpa1(15382) rat ... Hnrnpa1(29578) |
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¥ 3275.78
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