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IL-8 (77aa) (CXCL8) human，25UG，SRP3098-25UG，Sigma

销售价： ¥ 2929.63 / 件

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订货号： 0BR3884

品牌型号： Sigma SRP3098-25UG

货期：询货期

最小订货量： 1件

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商品介绍
规格参数
包装参数

产品介绍 Product Description

General description

Interleukin-8 (IL-8) is a proinflammatory CXC chemokine that can signal through the C-X-C motif chemokine receptors 1 and 2 (CXCR1 and 2). It is also called as C-X-C motif chemokine ligand 8 (CXCL8). IL-8 is secreted by monocytes and endothelial cells. The gene encoding IL-8 is localized on human chromosome 4q13.3. Recombinant human IL-8 (endothelial-derived) is an 8.9kDa protein containing 77 amino acid residues.

Application

IL-8 (77aa) (CXCL8) human has been used as a G protein-coupled receptor (GPCR) agonist.

Biochem/physiol Actions

Interleukin-8 (IL-8) chemoattracts and activates neutrophils. It is involved in guiding neutrophils and oligodendrocytes to sites of infection. The protein also stimulates angiogenesis and tumor growth. It is also associated with inflammatory diseases.

Physical form

Lyophilized with no additives.

Preparation Note

Centrifuge the vial prior to opening. Reconstitute in water to a concentration of 0.1-1.0 mg/ml. Do not vortex. This solution can be stored at 2-8°C for up to 1 week. For extended storage, it is recommended to further dilute in a buffer containing a carrier protein (example 0.1% BSA) and store in working aliquots at -20°C to -80°C.

Other Notes

AVLPRSAKEL RCQCIKTYSK PFHPKFIKEL RVIESGPHCA NTEIIVKLSD GRELCLDPKE NWVQRVVEKF LKRAENS

技术参数 Specifications

biological source	human
recombinant	expressed in E. coli
assay	≥98% (HPLC),≥98% (SDS-PAGE)
form	lyophilized
mol wt	8.9 kDa
packaging	pkg of 25 μg
technique(s)	cell culture \| mammalian: suitable
impurities	<0.1 EU/μg endotoxin, tested
color	white to off-white
UniProt accession no.	P10145
shipped in	wet ice
storage temp.	−20°C
Gene Information	human ... IL8(3576)

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