Monoclonal Anti-SET07 antibody produced in mouse,100UG,SAB1300134-100UG,Sigma

销售价: ¥ 3292.37 / 件
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订货号 0BR3138
品牌型号 Sigma SAB1300134-100UG
货期 询货期
最小订货量 1件
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产品介绍 Product Description

General description

SET07 is a histone methyltransferase that methylates Lys-20 of histone H4. H4 Lys-20 methylation represents a specific tag for epigenetic transcriptional repression. The nuclear SET07 protein, which associates with silent chromatin on euchromatic arms but shows no association with constitutive heterochromatin, prefers nucleosomes as substrate compared to free histones. It appears that SET07 may play a role in maintaining silent chromatin by preventing neighboring acetylation of H4 tail. Although the SET domain contains the active site of enzymatic activity, both sequences upstream and downstream of the SET domain are required for methyltransferase activity.


Immunogen

SET07 (AAF97812, N Terminal)
This antibody was raised using purified recombinant GST fusion protein encoding N-terminal of human SET07.


Physical form

Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.


技术参数 Specifications
biological sourcemouse
Quality Segment100
conjugateunconjugated
antibody formpurified immunoglobulin
antibody product typeprimary antibodies
clone43AT890, monoclonal
formbuffered aqueous solution
species reactivityhuman, mouse
technique(s)indirect ELISA: 1:1000,western blot: 1:100-1:500
isotypeIgG1
NCBI accession no.AAF97812
UniProt accession no.Q9NQR1
shipped indry ice
storage temp.−20°C
target post-translational modificationunmodified
Gene Informationhuman ... SET07(387893)
长度(mm)
宽度(mm)
高度(mm)
重量(kg)
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