- 商品介绍
- 规格参数
- 包装参数
Application
Triprolidine has been used as a H1 histaminergic inhibitor to study its effect on long-term potentiation (LTP) in tuberomammillary nucleus (TMN) neurons.
Biochem/physiol Actions
H1 histamine receptor antagonist.
Features and Benefits
This compound is featured on the Histamine Receptors page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.
This compound was developed by GlaxoSmithKline. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.
Preparation Note
Triprolidine hydrochloride is soluble in water at 50 mg/ml and yields a clear, colorless to yellow solution. It is also soluble in alcohol (1 in 1.5 of solvent) and chloroform (1 in less than 1 of solvent).
| Quality Segment | 200 |
| assay | ≥99% |
| solubility | alcohol: soluble 1 in 1.5 of solvent,chloroform: soluble 1 in less than 1 of solvent,H2O: soluble 50 mg/mL, clear, colorless to yellow |
| originator | GlaxoSmithKline |
| storage temp. | 2-8°C |
| SMILES string | CC(C=C1)=CC=C1/C(C2=NC=CC=C2)=C\CN3CCCC3.Cl |
| InChI | 1S/C19H22N2.ClH/c1-16-7-9-17(10-8-16)18(19-6-2-3-12-20-19)11-15-21-13-4-5-14-21;/h2-3,6-12H,4-5,13-15H2,1H3;1H/b18-11+; |
| InChI key | WYUYEJNGHIOFOC-NWBUNABESA-N |
| Gene Information | human ... HRH1(3269) |
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