- 商品介绍
- 规格参数
- 包装参数
Biochem/physiol Actions
EC23 is a synthetic, photostable all-trans retinoic acid (ATRA) analog/mimetic that targets RAR with greater affinity than ATRA (RARα/β/γ EC50 by cell-free TR-FRET binding assay = 3.7/3.3/16.8 with EC23 vs. 16.0/17.6/14.7 nM with ATRA) and does not bind retinoid x receptors (RXRs). EC23 induces differentiation of human pluripotent embryonic stem cells (0.1-10 μM) with a similar or better efficiency than ATRA.
Photostable all-trans retinoic acid (ATRA) mimetic that targets RAR with greater affinity and induces stem cells differentiation with better efficiency than ATRA.
| assay | ≥98% (HPLC) |
| form | powder |
| color | white to beige |
| solubility | DMSO: 2 mg/mL, clear |
| storage temp. | 2-8°C |
| SMILES string | OC(=O)c1ccc(cc1)C#Cc2cc3c(cc2)C(CCC3(C)C)(C)C |
| InChI | 1S/C23H24O2/c1-22(2)13-14-23(3,4)20-15-17(9-12-19(20)22)6-5-16-7-10-18(11-8-16)21(24)25/h7-12,15H,13-14H2,1-4H3,(H,24,25) |
| InChI key | OQVLOWLEEHYBJH-UHFFFAOYSA-N |
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¥ 2622.09
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¥ 1683.78
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¥ 1779.22
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¥ 1451.54
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¥ 9207.92
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¥ 6330.00
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¥ 3812.28
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¥ 2151.46
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¥ 1509.00
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¥ 2132.12
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