- 商品介绍
- 规格参数
- 包装参数
General description
Unc-51 like autophagy activating kinase 1 (ULK1) is a serine/threonine protein kinase which forms a component of the ULK1 protein kinase complex. This protein complex also contains the adaptor proteins ATG (autophagy-related) 13, RB1CC1/FIP200 (RB1-inducible coiled-coil 1), and ATG101. The gene encoding this protein is localized on human chromosome 12q24.33.
Application
GST-ULK1 has been used in in vitro kinase assay.
Biochem/physiol Actions
Unc-51 like autophagy activating kinase 1 (ULK1) protein kinase plays a crucial role in the control of autophagy initiation. This protein is responsible for activating a cascade of signaling pathways which results in the formation of phagosomes. ULK1 is also required for the control of the expression of key interferon-stimulated genes (ISGs).
Physical form
Supplied in 50mM Tris-HCl, pH 7.5, 150mM NaCl, 10mM glutathione, 0.1mM EDTA, 0.25mM DTT, 0.1mM PMSF, 25% glycerol.
Preparation Note
after opening, aliquot into smaller quantities and store at -70 °C. Avoid repeating handling and multiple freeze/thaw cycles
Legal Information
PRECISIO is a registered trademark of Merck KGaA, Darmstadt, Germany
| recombinant | expressed in baculovirus infected Sf9 cells |
| product line | PRECISIO® Kinase |
| assay | ≥70% (SDS-PAGE) |
| form | buffered aqueous glycerol solution |
| specific activity | 46-62 nmol/min·mg |
| mol wt | ~125 kDa |
| NCBI accession no. | BC111603 |
| shipped in | dry ice |
| storage temp. | −70°C |
| Gene Information | human ... ULK1(8408) |
| 长度(mm) | |
| 宽度(mm) | |
| 高度(mm) | |
| 重量(kg) |
-
¥ 1148.92
-
询价
-
询价
-
¥ 1451.54
-
询价
-
询价
-
询价
-
询价
-
¥ 5167.58
-
¥ 2268.97
-
¥ 1568.60
-
¥ 2307.00
-
¥ 4614.63
-
¥ 18741.69
-
询价
-
询价
-
询价
-
询价
-
询价
-
询价
微信小程序
7X24小时在线咨询