Anti-LAMP-2 antibody produced in rabbit，100UG，PRS3627-100UG，Sigma 供应商、价格、厂家、报价、规格参数

产品介绍 Product Description

General description

Lamp2 (lysosome-associated membrane protein gene)is located in the lysosomal lumen and lysosomal membrane. However upon chronic acidosis in the tumour microenvironment, it is found to be present in the plasma membrane.

Immunogen

a 17 amino acid peptide from near the center of human LAMP-2.

Application

Anti-LAMP-2 antibody has been used in immunofluorescence and western blot.
Applications in which this antibody has been used successfully, and the associated peer-reviewed papers, are given below.
Immunofluorescence (1 paper)

Biochem/physiol Actions

LAMP2 (lysosome-associated membrane protein gene) preserves lysosomal membranes from acid proteolysis. It serves as an acidity biomarker in spheroids and xenografts. It also has some role in maturation of autophagic vacuoles and cell-cell or cell-extracellular matrix adhesion. Reduction of LAMP2 (lysosome-associated membrane protein gene) can increase acidosis-mediated toxicity. Mutation in LAMP2 can cause cardiomyopathy in young patients.

Physical form

Solution in phosphate buffered saline containing 0.02% sodium azide

Other Notes

The action of this antibody can be blocked using blocking peptide SBP3627.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

技术参数 Specifications

biological source	rabbit
Quality Level	100
conjugate	unconjugated
antibody form	affinity isolated antibody
antibody product type	primary antibodies
clone	polyclonal
form	buffered aqueous solution
species reactivity	mouse, human
technique(s)	immunocytochemistry: suitable,indirect ELISA: suitable,western blot: suitable
UniProt accession no.	P17047
shipped in	dry ice
storage temp.	−20°C
target post-translational modification	unmodified
Gene Information	mouse ... Lamp2(16784)

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