- 商品介绍
- 规格参数
- 包装参数
Biochem/physiol Actions
Highly potent and selective platelet-activating factor (PAF) receptor antagonist
LAU-0901 is a highly potent and selective platelet-activating factor (PAF) receptor antagonist that is neuroprotective in experimental stroke, and protective in a variety of inflammation models. LAU-0901 blocks pro-inflammatory signaling. LAU-0901 demonstrated efficacy in a mouse model of glioblastoma multiforme (GBM) alone and in combination with Avastin.
| Quality Segment | 100 |
| assay | ≥98% (HPLC) |
| form | powder |
| color | white to beige |
| solubility | DMSO: 2 mg/mL, clear |
| storage temp. | 2-8°C |
| SMILES string | CC1C(C(OCCOC2=CC(Cl)=C(C=C2)Cl)=O)=C(NC(C)=C1C(OC(CN3CCOCC3)CN4CCOCC4)=O)C |
| InChI | 1S/C29H39Cl2N3O7/c1-19-26(28(35)40-15-14-39-22-4-5-24(30)25(31)16-22)20(2)32-21(3)27(19)29(36)41-23(17-33-6-10-37-11-7-33)18-34-8-12-38-13-9-34/h4-5,16,19,23,32H,6-15,17-18H2,1-3H3 |
| InChI key | WZWJKBCMEZITJW-UHFFFAOYSA-N |
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¥ 1148.92
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¥ 1563.36
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¥ 1573.49
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¥ 1866.29
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¥ 3442.25
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¥ 8520.40
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¥ 6330.00
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