Anti-SF3B1 Antibody, clone 4A3G9, Rabbit Monoclonal,100UL,SAB5702705-100UL,Sigma

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订货号 0BQ2550
品牌型号 Sigma SAB5702705-100UL
货期 询货期
最小订货量 1件
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产品介绍 Product Description

General description

This gene encodes subunit 1 of the splicing factor 3b protein complex. Splicing factor 3b, together with splicing factor 3a and a 12S RNA unit, forms the U2 small nuclear ribonucleoproteins complex (U2 snRNP). The splicing factor 3b/3a complex binds pre-mRNA upstream of the intron's branch site in a sequence independent manner and may anchor the U2 snRNP to the pre-mRNA. Splicing factor 3b is also a component of the minor U12-type spliceosome. The carboxy-terminal two-thirds of subunit 1 have 22 non-identical, tandem HEAT repeats that form rod-like, helical structures. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]


Immunogen

A synthetic peptide corresponding to a sequence within amino acids 1-100 of human SF3B1 (O75533).
PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.


Application

WB, IHC, IF/ICC


技术参数 Specifications
biological sourcerabbit
Quality Segment100
conjugateunconjugated
materialcolorless
clone4A3G9, monoclonal
formliquid
mol wt 146 kDa
species reactivityrat, human
concentration0.27 mg/mL
technique(s)immunofluorescence: 1:50 - 1:200,immunohistochemistry: 1:50 - 1:200,western blot: 1:500 - 1:2000
color colorless
isotypeIgG
immunogen sequenceMAKIAKTHEDIEAQIREIQGKKAALDEAQGVGLDSTGYYDQEIYGGSDSRFAGYVTSIAATELEDDDDDYSSSTSLLGQKKPGYHAPVALLNDIPQSTEQ
UniProt accession no.O75533
shipped inwet ice
storage temp.−20°C
target post-translational modificationunmodified
Gene Informationhuman ... SF3B1(23451)
长度(mm)
宽度(mm)
高度(mm)
重量(kg)
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