- 商品介绍
- 规格参数
- 包装参数
Biochem/physiol Actions
AZ1080 is a brain penetrant, orally bioavailable, potent and selective glycogen synthase kinase (GSK3) inhibitor that reduce pcdc1 (PD-1) transcription and expression. AZ1080 enhances CD8+ T-cell function in cancer, and is as effective as ant-PD-1 in controlling of B16 melanoma and EL4 lymphoma growth in mice.
Brain penetrant, orally bioavailable, potent and selective glycogen synthase kinase (GSK3) inhibitor that reduce pcdc1 (PD-1) transcription and expression
| Quality Segment | 100 |
| assay | ≥98% (HPLC) |
| form | powder |
| color | , Faint yellow to yellow brown |
| solubility | DMSO: 2 mg/mL, clear |
| storage temp. | -10 to -25°C |
| SMILES string | N4(CCOCC4)Cc1cnc(cc1)c2c3c([nH]c2O)ccc(c3)C#N |
| InChI | 1S/C19H18N4O2/c20-10-13-1-3-16-15(9-13)18(19(24)22-16)17-4-2-14(11-21-17)12-23-5-7-25-8-6-23/h1-4,9,11,22,24H,5-8,12H2 |
| InChI key | BLTVBQXJFVRPFK-UHFFFAOYSA-N |
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NNALGENE 180透明塑料管，透明，柔软，多用，经济，内径 x 外径x壁厚，1/4 x 1/2 x 1/8，英寸，每箱数量50，50/箱，8000-0080，Thermofisher，赛默飞世尔询价
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