- 商品介绍
- 规格参数
- 包装参数
General description
RBPJ is a transcriptional repressor that targets notch signaling. Studies have reported that it can activate the K14/vGPCR promoter of Kaposi′s sarcoma-associated herpesvirus (KSHV). Furthermore, RBPJ has also been implicated in the differentiation suppression of myogenic precursor cells.
Rabbit Anti-RBPJ antibody recognizes human, bovine, canine, and mouse RBPJ.
Immunogen
Synthetic peptide directed towards the C terminal region of human RBPSUH
Application
Rabbit Anti-RBPJ antibody can be used for western blot (0.25μg/ml) assays.
Biochem/physiol Actions
RBPSUH is a DNA binding protein that activates a full transcriptional response but only demonstrates partial anti-apoptotic activity. RTA-mediated redirection of RBPSUH activity from repression to activation is critical for lytic viral replication.
Physical form
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Other Notes
Synthetic peptide located within the following region: RPHCSAAGAILRANSSQVPPNESNTNSEGSYTNASTNSTSVTSSTATVVS
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
| biological source | rabbit |
| Quality Segment | 100 |
| conjugate | unconjugated |
| antibody form | affinity isolated antibody |
| antibody product type | primary antibodies |
| clone | polyclonal |
| form | buffered aqueous solution |
| mol wt | 56 kDa |
| species reactivity | dog, bovine, guinea pig, rabbit, rat, human, horse |
| concentration | 0.5 mg - 1 mg/mL |
| technique(s) | immunohistochemistry: suitable,immunoprecipitation (IP): suitable,western blot: suitable |
| NCBI accession no. | NP_005340 |
| UniProt accession no. | Q06330 |
| shipped in | wet ice |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| Gene Information | human ... RBPJ(3516) |
| 长度(mm) | |
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