Pitavastatin calcium,25MG,SML2473-25MG,Sigma

销售价: ¥ 2280.31 / 件
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订货号 : 0BP1797
品牌型号 : Sigma SML2473-25MG
货期 : 询货期
最小订货量 : 1件
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产品介绍 Product Description

Biochem/physiol Actions

HMG CoA reductase inhibitor
Pitavastatin calcium is a water-soluble inhibitor of hydroxymethylglutaryl-coenzyme A (HMG-CoA) reductase, the enzyme that catalyzes the conversion of HMG-CoA to mevalonic acid, the rate-limiting step in cholesterol biosynthesis. Pitavastatin calcium is antilipidemic and is used to reduce plasma cholesterol levels and prevent cardiovascular disease.


技术参数 Specifications
assay≥98% (HPLC)
formpowder
optical activity[α]/D +19 to +24°, c = 1 in acetonitrile: water (1:1)
storage conditiondesiccated
color white to beige
solubilityDMSO: 2 mg/mL, clear
storage temp.2-8°C
SMILES string[Ca+2].Fc5ccc(cc5)c6c7c(nc(c6\C=C\[C@@H](O)C[C@@H](O)CC(=O)[O-])C8CC8)cccc7.Fc1ccc(cc1)c2c3c(nc(c2\C=C\[C@@H](O)C[C@@H](O)CC(=O)[O-])C4CC4)cccc3
InChI1S/2C25H24FNO4.Ca/c2*26-17-9-7-15(8-10-17)24-20-3-1-2-4-22(20)27-25(16-5-6-16)21(24)12-11-18(28)13-19(29)14-23(30)31;/h2*1-4,7-12,16,18-19,28-29H,5-6,13-14H2,(H,30,31);/q;;+2/p-2/b2*12-11+;/t2*18-,19-;/m11./s1
InChI keyRHGYHLPFVJEAOC-FFNUKLMVSA-L
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