- 商品介绍
- 规格参数
- 包装参数
产品介绍
Product Description
Application
SCH-442416 has been used:
- as a selective adenosine A2A antagonist to study its effects on cyclic adenosine monophosphate (cAMP) production in T/C-28a2 chondrocytes or hFOB 1.19 osteoblasts
- as a presynaptic A2A receptor antagonists to study its effects on receptor blockade on δ9-Tetrahydrocannabinol (THC) self-administration in squirrel monkeys
- as a presynaptic A2A receptor antagonists to study its effects on cocaine-induced locomotion and cocaine-seeking in mice
Biochem/physiol Actions
SCH-442416 potent and selective Adenosine A2a antagonist. SCH-442416 is >10,000-fold selective for A2a compared to other adensosine receptors.
Features and Benefits
This compound is featured on the Adenosine Receptors page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.
技术参数
Specifications
| Quality Level | 100 |
| assay | ≥98% (HPLC) |
| form | powder |
| storage condition | desiccated |
| color | light tan to tan |
| solubility | DMSO: ≥20 mg/mL |
| storage temp. | 2-8°C |
| SMILES string | COc1ccc(CCCn2ncc3c2nc(N)n4nc(nc34)-c5ccco5)cc1 |
| InChI | 1S/C20H19N7O2/c1-28-14-8-6-13(7-9-14)4-2-10-26-18-15(12-22-26)19-23-17(16-5-3-11-29-16)25-27(19)20(21)24-18/h3,5-9,11-12H,2,4,10H2,1H3,(H2,21,24) |
| InChI key | AEULVFLPCJOBCE-UHFFFAOYSA-N |
| 长度(mm) | |
| 宽度(mm) | |
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| 重量(kg) |
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